Attention-deficit hyperactivity disorder (ADHD) is a heterogenous behavioral disorder with inattention, hyperactivity and impulsivity symptoms, indicating the important implication of identifying biotypes and its epicenters in understanding disease’s pathogenesis. The study investigated the neuromorphic heterogeneity relating to transcriptional similarity architecture in ADHD, and further analyzed the epicenters of network-spreading in each ADHD biotype and their correlations with clinical…